Darier Disease
Histopathology:
- Columns of parakeratosis above acantholytic and dyskeratotic cells (red arrow)
- Many areas of suprabasal clefts in epidermis (blue arrow)
- Acantholytic dyskeratosis (orange arrow)
- Corpus ronds: acantholytic dyskeratotic cells in granular and spinous layers (yellow circle)
- Grains: acantholytic parakeratotic cells (green circle)
- Scanty perivascular lymphocytic cells infiltrate in superficial dermis