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Case prepared by Dr Viren Vaghasiya and Dr Jitendra Nasit Gross Pathology: – A single well-circumscribed smooth nodular mass of approximately 4 cm, with a solid tan-yellowish cut surface. Single small point show more brownish color. Single small separate strip of dura is also reveived (not shown here). Histopathology: – The neoplastic proliferation of variable-size…
Gross Pathology: Granular cell tumor of the breast Histopathology: – Solid alveolar arrangement of the large cells with abundant granular eosinophilic cytoplasm and round bland nuclei. Occasional cells show small distinct nucleoli. Cell borders are not well-appreciated in the above case probably due to poor fixation and microtomy. Focal mild atypia is seen. – Variable…
Syringoma Histopathology: – The dermis shows small, rounded nests (orange arrow) and few compressed angulated (coma/tadpole-shape) tubular ducts (coma/tadpole-shape) (red arrow) and cord-like structures (blue arrow), in a dense collagenised-fibrotic stroma. – Some of the tubules show small lumen filled with pale eosinophilic material (green arrow). Tubules show inner bland cuboidal and peripheral myoepithelial cells…
Middle ear neuroendocrine tumour/Middle Ear Adenoma (old term) Histopathology: – Surface mucosa appears unremarkable. – Mainly solid nests and trabecular growth patterns in a background of loose fibrous stroma, with pseudo-infiltrative looking pattern (carcinoid like look). – The single area shows a large glandular pattern. – Neoplastic cells show monotonous round to ovoid nuclei with…
Case prepared by Dr Viren Vaghasiya and Dr Jitendra Nasit Cellular Blue nevus Grossly the lesion is circumscribed bluish-black nodule of around 15mm. The cut surface shows a homogenous brownish-black area. Histopathology: – Relatively circumscribed lobular nested and dumbbell-shaped dermal-based lesion consisting of a melanocytic cells proliferation. – The neoplasm shows two characteristics features: 1….
Continue reading… “A male in his 30s presents with a blue black nodule on the heal of his foot” »
Cytology images: Histopathology Images: Anaplastic/Undifferentiated Carcinoma of the Thyroid gland Histopathology: – Pleomorphic spindle and giant cells invade the normal thyroid gland, capsule, and extrathyroidal extension into adjacent adipose tissue (brown arrow). The parathyroid gland appears free from the tumor. – A mixture of various cell types – pleomorphic spindle cells, epithelioid/rhabdoid-like cells (yellow square),…
Superficial Acral Fibromyxoma/ Digital Fibromyxoma Histopathology: Practical Points of Pathoclinics: Differentiating points Acral fibromyxoma Dermatofibrosarcoma protuberans Site Classic locations are fingers or toes; subungual or periungual areas-nail bed region. Uncommon at fingers or toes. Extension into subcutaneous tissue is common. Histopathology Variably cellular lobulated neoplasm, with even/random distribution of bland spindle cells to stellate-shaped fibroblastic…
Continue reading… “42-year-old male with a slow growing swelling over great toe.” »
