A some around 58-year-old male presents with a rapidly enlarging thyroid mass. Ultrasound guided fine needle aspiration cytology suggests undifferentiated malignant tumor, (TBSRTC, diagnostic category VI). Surgical resection specimen for further evaluation.
Cytology images: Histopathology Images: Anaplastic/Undifferentiated Carcinoma of the Thyroid gland Histopathology: – Pleomorphic spindle and giant cells invade the normal thyroid gland, capsule, and extrathyroidal extension into adjacent adipose tissue (brown arrow). The parathyroid gland appears free from the tumor. – A mixture of various cell types – pleomorphic spindle cells, epithelioid/rhabdoid-like cells (yellow square),…