Ochronosis
Histopathology: Histologic features of both endogenous ochronosis (alkaptonuria) and exogenous ochronosis are similar. Curved banana shaped or rounded, yellow-brown to greyish-black coloured, ochronotic bodies/ochre pigmentation, affecting degenerating collagen and elastic fibre (green area), in the superficial dermis and connective tissue. Pigment incontinence with increased melanin in dermis and macrophages (blue area) Epidermis appears unremarkable. Features…